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Study protocol of Prednisone in episodic Cluster Headache (PredCH): a randomized, double-blind, placebo-controlled parallel group trial to evaluate the efficacy and safety of oral prednisone as an add-on therapy in the prophylactic treatment of episodic cluster headache with verapamil

BACKGROUND: Episodic cluster headache (ECH) is a primary headache disorder that severely impairs patient’s quality of life. First-line therapy in the initiation of a prophylactic treatment is verapamil. Due to its delayed onset of efficacy and the necessary slow titration of dosage for tolerability...

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Autors principals: Holle, Dagny, Burmeister, Jan, Scherag, André, Ose, Claudia, Diener, Hans-Christoph, Obermann, Mark
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729502/
https://ncbi.nlm.nih.gov/pubmed/23889923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2377-13-99
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