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An Adaptable Luminescence Resonance Energy Transfer Assay for Measuring and Screening Protein-Protein Interactions and their Inhibition

Protein–protein interactions (PPIs) are central to biological processes and represent an important class of therapeutic targets. Here we show that the interaction between FK506 binding protein 12 fused to green fluorescent protein (GFP-FKBP) and the rapamycin-binding domain of mTor fused to Escheric...

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Detalhes bibliográficos
Main Authors: Yapici, Engin, Reddy, D. Rajasekhar, Miller, Lawrence W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729432/
https://ncbi.nlm.nih.gov/pubmed/22271654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201100710
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