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Neutral sphingomyelinase 2 modulates cytotoxic effects of protopanaxadiol on different human cancer cells

BACKGROUND: Some of ginsenosides, root extracts from Panax ginseng, exert cytotoxicity against cancer cells through disruption of membrane subdomains called lipid rafts. Protopanaxadiol (PPD) exhibits the highest cytotoxic effect among 8 ginsenosides which we evaluated for anti-cancer activity. We i...

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Detalhes bibliográficos
Main Authors: Park, Bonggoo, Lee, Yong-Moon, Kim, Jae-Sung, Her, Youl, Kang, Ju Hee, Oh, Seung-Hyun, Kim, Hwan-Mook
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729373/
https://ncbi.nlm.nih.gov/pubmed/23889969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-13-194
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