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CD4(+) T cell depletion in HIV infection: mechanisms of immunological failure

The hallmark of acquired immunodeficiency syndrome (AIDS) pathogenesis is a progressive depletion of CD4(+) T-cell populations in close association with progressive impairment of cellular immunity and increasing susceptibility to opportunistic infections (OI). Disease progression in untreated human...

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Bibliografiske detaljer
Main Authors: Okoye, Afam A., Picker, Louis J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729334/
https://ncbi.nlm.nih.gov/pubmed/23772614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12066
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