Determination of the Transport Rate of Xenobiotics and Nanomaterials Across the Placenta using the ex vivo Human Placental Perfusion Model

Decades ago the human placenta was thought to be an impenetrable barrier between mother and unborn child. However, the discovery of thalidomide-induced birth defects and many later studies afterwards proved the opposite. Today several harmful xenobiotics like nicotine, heroin, methadone or drugs as...

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Bibliographic Details
Main Authors: Grafmüller, Stefanie, Manser, Pius, Krug, Harald F., Wick, Peter, von Mandach, Ursula
Format: Artigo
Language:Inglês
Published: MyJove Corporation 2013
Subjects:
Biomedical Engineering
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729252/
https://ncbi.nlm.nih.gov/pubmed/23851364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/50401
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