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Cloning, expression, purification and preliminary X-ray diffraction studies of a novel AB(5) toxin

AB(5) toxins are key virulence factors found in a range of pathogenic bacteria. AB(5) toxins consist of two components: a pentameric B subunit that targets eukaryotic cells by binding to glycans located on the cell surface and a catalytic A subunit that disrupts host cellular function following inte...

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Autori principali: Ng, Natasha, Littler, Dene, Le Nours, Jérôme, Paton, Adrienne W., Paton, James C., Rossjohn, Jamie, Beddoe, Travis
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Union of Crystallography 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729173/
https://ncbi.nlm.nih.gov/pubmed/23908042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309113018927
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