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Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes.

The three classes of enzymes which inactivate aminoglycosides and lead to bacterial resistance are reviewed. DNA hybridization studies have shown that different genes can encode aminoglycoside-modifying enzymes with identical resistance profiles. Comparisons of the amino acid sequences of 49 aminogl...

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Bibliografische gegevens
Hoofdauteurs: Shaw, K J, Rather, P N, Hare, R S, Miller, G H
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1993
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC372903/
https://ncbi.nlm.nih.gov/pubmed/8385262
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