CCR5 promoter polymorphism determines macrophage CCR5 density and magnitude of HIV-1 propagation in vitro

The common CCR5 promoter polymorphism at position –2459 (A/G) has been associated with differences in the rate of progression to AIDS, where HIV-1-infected individuals with the CCR5 –2459 G/G genotype exhibit slower disease progression than those with the A/A genotype. Mechanisms underlying the rela...

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Hlavní autoři: Salkowitz, Janelle R., Bruse, Shannon E., Meyerson, Howard, Valdez, Hernan, Mosier, Donald E., Harding, Clifford V., Zimmerman, Peter A., Lederman, Michael M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728895/
https://ncbi.nlm.nih.gov/pubmed/14499246
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