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Chondrogenic capacity and alterations in hyaluronan synthesis of cultured human osteoarthritic chondrocytes

During osteoarthritis there is a disruption and loss of the extracellular matrix of joint cartilage, composed primarily of type II collagen, aggrecan and hyaluronan. In young patients, autologous chondrocyte implantation can be used to repair cartilage defects. However, for more elderly patients wit...

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Autors principals: Ono, Yohei, Sakai, Tadahiro, Hiraiwa, Hideki, Hamada, Takashi, Omachi, Takaaki, Nakashima, Motoshige, Ishizuka, Shinya, Matsukawa, Tetsuya, Knudson, Warren, Knudson, Cheryl B., Ishiguro, Naoki
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728838/
https://ncbi.nlm.nih.gov/pubmed/23702485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2013.05.052
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