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Plasmodium falciparum erythrocyte invasion through glycophorin C and selection for Gerbich negativity in human populations

Geographic overlap between malaria and the occurrence of mutant hemoglobin and erythrocyte surface proteins has indicated that polymorphisms in human genes have been selected by severe malaria(1,2). Deletion of exon 3 in the glycophorin C gene (called GYPCΔex3 here) has been found in Melanesians; th...

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Detalhes bibliográficos
Main Authors: Maier, Alexander G., Duraisingh, Manoj T., Reeder, John C., Patel, Sheral S., Kazura, James W., Zimmerman, Peter A., Cowman, Alan F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728825/
https://ncbi.nlm.nih.gov/pubmed/12469115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm807
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