Glial Scar Borders Are Formed by Newly Proliferated, Elongated Astrocytes That Interact to Corral Inflammatory and Fibrotic Cells via STAT3-Dependent Mechanisms after Spinal Cord Injury

Astroglial scars surround damaged tissue after trauma, stroke, infection, or autoimmune inflammation in the CNS. They are essential for wound repair, but also interfere with axonal regrowth. A better understanding of the cellular mechanisms, regulation, and functions of astroglial scar formation is...

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Detalhes bibliográficos
Main Authors: Wanner, Ina B., Anderson, Mark A., Song, Bingbing, Levine, Jaclynn, Fernandez, Ana, Gray-Thompson, Zachary, Ao, Yan, Sofroniew, Michael V.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728693/
https://ncbi.nlm.nih.gov/pubmed/23904622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2121-13.2013
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