Protective Efficacy of VP1-Specific Neutralizing Antibody Associated with a Reduction of Viral Load and Pro-Inflammatory Cytokines in Human SCARB2-Transgenic Mice

Hand-foot-mouth diseases (HFMD) caused by enterovirus 71 (EV71) and coxsackievirus 16 (CVA16) in children have now become a severe public health issue in the Asian-Pacific region. Recently we have successfully developed transgenic mice expressing human scavenger receptor class B member 2 (hSCARB2, a...

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Hlavní autoři: Chang, Hsuen-Wen, Lin, Yi-Wen, Ho, Hui-Min, Lin, Min-Han, Liu, Chia-Chyi, Shao, Hsiao-Yun, Chong, Pele, Sia, Charles, Chow, Yen-Hung
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728341/
https://ncbi.nlm.nih.gov/pubmed/23936115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069858
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