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Haploinsufficiency of Akt1 Prolongs the Lifespan of Mice

There is increasing evidence that nutrient-sensing machinery is critically involved in the regulation of aging. The insulin/insulin-like growth factor-1 signaling pathway is the best-characterized pathway with an influence on longevity in a variety of organisms, ranging from yeast to rodents. Reduce...

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Detalhes bibliográficos
Main Authors: Nojima, Aika, Yamashita, Masakatsu, Yoshida, Yohko, Shimizu, Ippei, Ichimiya, Harumi, Kamimura, Naomi, Kobayashi, Yoshio, Ohta, Shigeo, Ishii, Naoaki, Minamino, Tohru
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728301/
https://ncbi.nlm.nih.gov/pubmed/23935948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069178
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