Whole Cell Screen for Inhibitors of pH Homeostasis in Mycobacterium tuberculosis

Bacterial pathogens like Mycobacterium tuberculosis (Mtb) encounter acidic microenvironments in the host and must maintain their acid-base homeostasis to survive. A genetic screen identified two Mtb strains that cannot control intrabacterial pH (pH(IB)) in an acidic environment; infection with eithe...

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Detalhes bibliográficos
Main Authors: Darby, Crystal M., Ingólfsson, Helgi I., Jiang, Xiuju, Shen, Chun, Sun, Mingna, Zhao, Nan, Burns, Kristin, Liu, Gang, Ehrt, Sabine, Warren, J. David, Anderson, Olaf S., Brickner, Steven J., Nathan, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728290/
https://ncbi.nlm.nih.gov/pubmed/23935911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068942
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