Whole Cell Screen for Inhibitors of pH Homeostasis in Mycobacterium tuberculosis

Bacterial pathogens like Mycobacterium tuberculosis (Mtb) encounter acidic microenvironments in the host and must maintain their acid-base homeostasis to survive. A genetic screen identified two Mtb strains that cannot control intrabacterial pH (pH(IB)) in an acidic environment; infection with eithe...

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Bibliografski detalji
Glavni autori: Darby, Crystal M., Ingólfsson, Helgi I., Jiang, Xiuju, Shen, Chun, Sun, Mingna, Zhao, Nan, Burns, Kristin, Liu, Gang, Ehrt, Sabine, Warren, J. David, Anderson, Olaf S., Brickner, Steven J., Nathan, Carl
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728290/
https://ncbi.nlm.nih.gov/pubmed/23935911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068942
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