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Assessing acute systemic effects of an inhaled drug with serial echocardiography: a placebo-controlled comparison of inhaled and intravenous dihydroergotamine

OBJECTIVE: MAP0004 is an investigational product which delivers dihydroergotamine (DHE) through the lung via a breath-synchronized metered dose inhaler. The objective of this study was to compare the acute effects of orally inhaled and intravenous (IV) DHE to placebo on maximum change and area under...

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Autores principales: Noveck, Robert J, Douglas, Pamela S, Chow, Shein-Chung, Mangum, Barry, Kori, Shashidhar, Kellerman, Donald J
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3728267/
https://ncbi.nlm.nih.gov/pubmed/23926420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S44093
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