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Recent progress in the biology and physiology of sirtuins
The sirtuins are a highly conserved family of NAD(+)-dependent enzymes that regulate lifespan in lower organisms. Recently, the mammalian sirtuins have been connected to an ever widening circle of activities that encompass cellular stress resistance, genomic stability, tumorigenesis and energy metab...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3727385/ https://ncbi.nlm.nih.gov/pubmed/19641587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08197 |
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