Arthritis severity locus Cia4 is an early regulator of IL-6, IL-1β, and NF-κB activators' expression in pristane-induced arthritis

Cia4 is a locus on rat chromosome 7 that regulates disease severity and joint damage in models of rheumatoid arthritis, including pristane-induced arthritis (PIA). To identify molecular processes regulated by Cia4, synovial tissues from MHC-identical DA (severe erosive) and DA.F344(Cia4) congenics (...

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Detalhes bibliográficos
Main Authors: Brenner, Max, Laragione, Teresina, Gulko, Pércio S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Molecular Genetics of Complex Traits
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3727023/
https://ncbi.nlm.nih.gov/pubmed/23695883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00029.2013
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