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Ca(2+)-pumping impairment during repetitive fatiguing contractions in single myofibers: role of cross-bridge cycling

The energy cost of contractions in skeletal muscle involves activation of both actomyosin and sarcoplasmic reticulum (SR) Ca(2+)-pump (SERCA) ATPases, which together determine the overall ATP demand. During repetitive contractions leading to fatigue, the relaxation rate and Ca(2+) pumping become slo...

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Detalhes bibliográficos
Main Authors: Nogueira, Leonardo, Shiah, Amy A., Gandra, Paulo G., Hogan, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726998/
https://ncbi.nlm.nih.gov/pubmed/23678027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00178.2013
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