Apolipoprotein A-1 mimetic D-4F enhances isoflurane-induced eNOS signaling and cardioprotection during acute hyperglycemia

Acute hyperglycemia (AHG) decreases the availability of nitric oxide (NO) and impairs anesthetic preconditioning (APC)-elicited protection against myocardial infarction. We investigated whether D-4F, an apolipoprotein A-1 mimetic, rescues the myocardium by promoting APC-induced endothelial NO signal...

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Autores principales: Baotic, Ines, Ge, Zhi-Dong, Sedlic, Filip, Coon, Adrian, Weihrauch, Dorothee, Warltier, David C., Kersten, Judy R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2013
Materias:
Integrative Cardiovascular Physiology and Pathophysiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726953/
https://ncbi.nlm.nih.gov/pubmed/23666677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00850.2012
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