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Serum markers of the extracellular matrix remodeling reflect antifibrotic therapy in bile-duct ligated rats
Background: Progression of liver fibrosis is characterized by synthesis and degradation of extracellular matrix (ECM). Matrix-metalloproteinases (MMP) cleave collagen fibers at a specific site and thereby generate soluble fragments of ECM (neo-epitopes). The levels of these neo-epitopes might reflec...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726835/ https://ncbi.nlm.nih.gov/pubmed/23908632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2013.00195 |
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