Histone Demethylase Retinoblastoma Binding Protein 2 is Overexpressed in Hepatocellular Carcinoma and Negatively Regulated by hsa-miR-212

BACKGROUND: The H3K4 demethylase retinoblastoma binding protein 2 (RBP2) is involved in the pathogenesis of gastric cancer, but its role and regulation in hepatocellular carcinoma (HCC) is unknown. We determined the function of RBP2 and its regulation in HCC in vitro and in human tissues. METHODS: W...

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Detalhes bibliográficos
Main Authors: Liang, Xiuming, Zeng, Jiping, Wang, Lixiang, Fang, Ming, Wang, Qing, Zhao, Min, Xu, Xia, Liu, Zhifang, Li, Wenjuan, Liu, Shili, Yu, Han, Jia, Jihui, Chen, Chunyan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726779/
https://ncbi.nlm.nih.gov/pubmed/23922798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069784
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