Tryptase Activation of Immortalized Human Urothelial Cell Mitogen-Activated Protein Kinase

The pathogenesis of interstitial cystitis/painful bladder syndrome (IC/PBS) is multifactorial, but likely involves urothelial cell dysfunction and mast cell accumulation in the bladder wall. Activated mast cells in the bladder wall release several inflammatory mediators, including histamine and tryp...

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Main Authors: Marentette, John O., Hauser, Paul J., Hurst, Robert E., Klumpp, David J., Rickard, Alice, McHowat, Jane
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726738/
https://ncbi.nlm.nih.gov/pubmed/23922867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069948
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