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Notch1 Signaling Regulates the Proliferation and Self-Renewal of Human Dental Follicle Cells by Modulating the G1/S Phase Transition and Telomerase Activity

Multipotent human dental follicle cells (HDFCs) have been intensively studied in periodontal regeneration research, yet the role of Notch1 in HDFCs has not been fully understood. The aim of the current study is to explore the role of Notch1 signaling in HDFCs self-renewal and proliferation. HDFCs we...

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Detalhes bibliográficos
Main Authors: Chen, Xuepeng, Zhang, Tianhou, Shi, Jiejun, Xu, Ping, Gu, Zexu, Sandham, Andrew, Yang, Lei, Ye, Qingsong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726724/
https://ncbi.nlm.nih.gov/pubmed/23922876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0069967
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