MicroRNA-224 Targets SMAD Family Member 4 to Promote Cell Proliferation and Negatively Influence Patient Survival

MicroRNA-224 (miR-224) is frequently over-expressed in liver and colorectal cancers. We and others have previously described the role of miR-224 over-expression in cell proliferation in vitro but we have yet to identify the relevant miR-224 direct target. In this study, we further demonstrated that...

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Detalhes bibliográficos
Main Authors: Wang, Yu, Ren, Jianwei, Gao, Yun, Ma, Joel Z. I., Toh, Han Chong, Chow, Pierce, Chung, Alexander Y. F., Ooi, London L. P. J., Lee, Caroline G. L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726696/
https://ncbi.nlm.nih.gov/pubmed/23922662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068744
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