Prognostic Significance of ESR1 Gene Amplification, mRNA/Protein Expression and Functional Profiles in High-Risk Early Breast Cancer: A Translational Study of the Hellenic Cooperative Oncology Group (HeCOG)

BACKGROUND: Discrepant data have been published on the incidence and prognostic significance of ESR1 gene amplification in early breast cancer. PATIENTS AND METHODS: Formalin-fixed paraffin-embedded tumor blocks were collected from women with early breast cancer participating in two HeCOG adjuvant t...

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Main Authors: Pentheroudakis, George, Kotoula, Vassiliki, Eleftheraki, Anastasia G., Tsolaki, Eleftheria, Wirtz, Ralph M., Kalogeras, Konstantine T., Batistatou, Anna, Bobos, Mattheos, Dimopoulos, Meletios A., Timotheadou, Eleni, Gogas, Helen, Christodoulou, Christos, Papadopoulou, Kyriaki, Efstratiou, Ioannis, Scopa, Chrisoula D., Papaspyrou, Irene, Vlachodimitropoulos, Dimitrios, Linardou, Helena, Samantas, Epaminontas, Pectasides, Dimitrios, Pavlidis, Nicholas, Fountzilas, George
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726626/
https://ncbi.nlm.nih.gov/pubmed/23923010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070634
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