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Alternative splicing the Neurofibromatosis type I pre-mRNA
Neurofibromatosis type I (NF1) is a common genetic disease that affects 1 in 3,500 individuals. The disease is completely penetrant but shows variable phenotypic expression in patients. NF1 is a large gene, and its pre-mRNA undergoes alternative splicing. The NF1 protein, neurofibromin, has a myriad...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726530/ https://ncbi.nlm.nih.gov/pubmed/22115364 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20110060 |
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