β-Keto esters from ketones and ethyl chloroformate: a rapid, general, efficient synthesis of pyrazolones and their antimicrobial, in silico and in vitro cytotoxicity studies

BACKGROUND: Pyrazolones are traditionally synthesized by the reaction of β-keto esters with hydrazine and its derivatives. There are methods to synthesize β-keto esters from esters and aldehydes, but these methods have main limitation in varying the substituents. Often, there are a number of methods...

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Main Authors: Ragavan, Ramasamy Venkat, Kumar, Kalavathi Murugan, Vijayakumar, Vijayaparthasarathi, Sarveswari, Sundaramoorthy, Ramaiah, Sudha, Anbarasu, Anand, Karthikeyan, Sivashanmugam, Giridharan, Periyasamy, Kumari, Nalilu Suchetha
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726461/
https://ncbi.nlm.nih.gov/pubmed/23870758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2191-2858-3-6
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