Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish

BACKGROUND: NEUROG3 is a key regulator of pancreatic endocrine cell differentiation in mouse, essential for the generation of all mature hormone producing cells. It is repressed by Notch signaling that prevents pancreatic cell differentiation by maintaining precursors in an undifferentiated state. R...

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Autores principales: Flasse, Lydie C, Pirson, Justine L, Stern, David G, Von Berg, Virginie, Manfroid, Isabelle, Peers, Bernard, Voz, Marianne L
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726459/
https://ncbi.nlm.nih.gov/pubmed/23835295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-11-78
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