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Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish
BACKGROUND: NEUROG3 is a key regulator of pancreatic endocrine cell differentiation in mouse, essential for the generation of all mature hormone producing cells. It is repressed by Notch signaling that prevents pancreatic cell differentiation by maintaining precursors in an undifferentiated state. R...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BioMed Central
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726459/ https://ncbi.nlm.nih.gov/pubmed/23835295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-11-78 |
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