Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish

BACKGROUND: NEUROG3 is a key regulator of pancreatic endocrine cell differentiation in mouse, essential for the generation of all mature hormone producing cells. It is repressed by Notch signaling that prevents pancreatic cell differentiation by maintaining precursors in an undifferentiated state. R...

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Autors principals: Flasse, Lydie C, Pirson, Justine L, Stern, David G, Von Berg, Virginie, Manfroid, Isabelle, Peers, Bernard, Voz, Marianne L
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726459/
https://ncbi.nlm.nih.gov/pubmed/23835295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-11-78
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