Comparative Study of Two Box H/ACA Ribonucleoprotein Pseudouridine-Synthases: Relation between Conformational Dynamics of the Guide RNA, Enzyme Assembly and Activity

Multiple RNA-guided pseudouridine synthases, H/ACA ribonucleoprotein particles (RNPs) which contain a guide RNA and four proteins, catalyze site-specific post-transcriptional isomerization of uridines into pseudouridines in substrate RNAs. In archaeal particles, the guide small RNA (sRNA) is anchore...

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Bibliographische Detailangaben
Hauptverfasser: Fourmann, Jean-Baptiste, Tillault, Anne-Sophie, Blaud, Magali, Leclerc, Fabrice, Branlant, Christiane, Charpentier, Bruno
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726423/
https://ncbi.nlm.nih.gov/pubmed/23922977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070313
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