Spatiotemporal Expression of Matrix Metalloproteinases (MMPs) is Regulated by the Ca(2+)-Signal Transducer S100A4 in the Pathogenesis of Thoracic Aortic Aneurysm

AIMS: This study investigated whether S100A4 plays a potential role in the formation of thoracic aortic aneurysm (TAA). METHODS AND RESULTS: The thoracic aortas of male Sprague-Dawley rats were exposed to 0.5 M CaCl2 or normal saline (NaCl). Animals were euthanized at specified time-points (2, 4, an...

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Detalhes bibliográficos
Main Authors: Cao, Jiumei, Geng, Liang, Wu, Qihong, Wang, Wei, Chen, Qiujing, Lu, Lin, Shen, Weifeng, Chen, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726393/
https://ncbi.nlm.nih.gov/pubmed/23922901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070057
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