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Mechanistic Insights into the Neutralization of Cytotoxic Abrin by the Monoclonal Antibody D6F10

Abrin, an A/B toxin obtained from the Abrus precatorius plant is extremely toxic and a potential bio-warfare agent. Till date there is no antidote or vaccine available against this toxin. The only known neutralizing monoclonal antibody against abrin, namely D6F10, has been shown to rescue the toxici...

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Detalhes bibliográficos
Main Authors: Bagaria, Shradha, Ponnalagu, Devasena, Bisht, Shveta, Karande, Anjali A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726390/
https://ncbi.nlm.nih.gov/pubmed/23922965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070273
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