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Mechanistic Insights into the Neutralization of Cytotoxic Abrin by the Monoclonal Antibody D6F10

Abrin, an A/B toxin obtained from the Abrus precatorius plant is extremely toxic and a potential bio-warfare agent. Till date there is no antidote or vaccine available against this toxin. The only known neutralizing monoclonal antibody against abrin, namely D6F10, has been shown to rescue the toxici...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bagaria, Shradha, Ponnalagu, Devasena, Bisht, Shveta, Karande, Anjali A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726390/
https://ncbi.nlm.nih.gov/pubmed/23922965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070273
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