Characterization of the Human Platelet α-Adrenergic Receptor: CORRELATION OF [(3)H] DIHYDROERGOCRYPTINE BINDING WITH AGGREGATION AND ADENYLATE CYCLASE INHIBITION

Human platelets aggregate and undergo a release reaction when incubated with catecholamines. Indirect evidence indicates that these events are mediated through α-adrenergic receptors. We used [(3)H]dihydroergocryptine, an α-adrenergic antagonist, to identify binding sites on platelets that have the...

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Autores principales: Alexander, R. Wayne, Cooper, Barry, Handin, Robert I.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1978
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC372633/
https://ncbi.nlm.nih.gov/pubmed/207726
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