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Enzyme-activatable imaging probe reveals enhanced neutrophil elastase activity in tumors following photodynamic therapy

We demonstrate the use of an enzyme-activatable fluorogenic probe, Neutrophil Elastase 680 FAST (NE680), for in vivo imaging of neutrophil elastase (NE) activity in tumors subjected to photodynamic therapy (PDT). NE protease activity was assayed in SCC VII and EMT6 tumors established in C3H and BALB...

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Detaylı Bibliyografya
Asıl Yazarlar: Mitra, Soumya, Modi, Kshitij D., Foster, Thomas H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society of Photo-Optical Instrumentation Engineers 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726228/
https://ncbi.nlm.nih.gov/pubmed/23897439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.JBO.18.10.101314
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