Circulating Human Antibody-Secreting Cells during Vaccinations and Respiratory Viral Infections Are Characterized by High Specificity and Lack of Bystander Effect

Surges of serum antibodies after immunization and infection are highly specific for the offending antigen, and recent studies demonstrate that vaccines induce transient increases in circulating antibody-secreting cells (ASCs). These ASCs are highly enriched but not universally specific for the immun...

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Autori principali: Lee, F. Eun-Hyung, Halliley, Jessica L., Walsh, Edward E., Moscatiello, Andrew P., Kmush, Brittany L., Falsey, Ann R., Randall, Troy D., Kaminiski, Denise A., Miller, Richard K., Sanz, Iñaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726212/
https://ncbi.nlm.nih.gov/pubmed/21441455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002932
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