An iPS Cell Line From Human Pancreatic Ductal Adenocarcinoma Undergoes Early to Invasive Stages of Pancreatic Cancer Progression

Pancreatic ductal adenocarcinoma (PDAC) carries a dismal prognosis and lacks a human cell model of early disease progression. When human PDAC cells are injected into immunodeficient mice, they generate advanced stage cancer. We hypothesized that if human PDAC cells were converted to pluripotency and...

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Autores principales: Kim, Jungsun, Hoffman, John P., Alpaugh, R. Katherine, Rhim, Andrew D., Reichert, Maximilian, Stanger, Ben Z., Furth, Emma E., Sepulveda, Antonia R., Yuan, Chao-Xing, Won, Kyoung-Jae, Donahue, Greg, Sands, Jessica, Gumbs, Andrew A., Zaret, Kenneth S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726210/
https://ncbi.nlm.nih.gov/pubmed/23791528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.05.036
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