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Recent molecular discoveries in angiogenesis and antiangiogenic therapies in cancer

Four decades ago, angiogenesis was recognized as a therapeutic target for blocking cancer growth. Because of its importance, VEGF has been at the center stage of antiangiogenic therapy. Now, several years after FDA approval of an anti-VEGF antibody as the first antiangiogenic agent, many patients wi...

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Bibliographic Details
Main Authors: Welti, Jonathan, Loges, Sonja, Dimmeler, Stefanie, Carmeliet, Peter
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726176/
https://ncbi.nlm.nih.gov/pubmed/23908119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70212
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