ARHGDIA mutations cause nephrotic syndrome via defective RHO GTPase signaling

Nephrotic syndrome (NS) is divided into steroid-sensitive (SSNS) and -resistant (SRNS) variants. SRNS causes end-stage kidney disease, which cannot be cured. While the disease mechanisms of NS are not well understood, genetic mapping studies suggest a multitude of unknown single-gene causes. We comb...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gee, Heon Yung, Saisawat, Pawaree, Ashraf, Shazia, Hurd, Toby W., Vega-Warner, Virginia, Fang, Humphrey, Beck, Bodo B., Gribouval, Olivier, Zhou, Weibin, Diaz, Katrina A., Natarajan, Sivakumar, Wiggins, Roger C., Lovric, Svjetlana, Chernin, Gil, Schoeb, Dominik S., Ovunc, Bugsu, Frishberg, Yaacov, Soliman, Neveen A., Fathy, Hanan M., Goebel, Heike, Hoefele, Julia, Weber, Lutz T., Innis, Jeffrey W., Faul, Christian, Han, Zhe, Washburn, Joseph, Antignac, Corinne, Levy, Shawn, Otto, Edgar A., Hildebrandt, Friedhelm
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726174/
https://ncbi.nlm.nih.gov/pubmed/23867502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69134
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados