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Atrial natriuretic peptide is negatively regulated by microRNA-425

Numerous common genetic variants have been linked to blood pressure, but no underlying mechanism has been elucidated. Population studies have revealed that the variant rs5068 (A/G) in the 3′ untranslated region of NPPA, the gene encoding atrial natriuretic peptide (ANP), is associated with blood pre...

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Detalhes bibliográficos
Main Authors: Arora, Pankaj, Wu, Connie, Khan, Abigail May, Bloch, Donald B., Davis-Dusenbery, Brandi N., Ghorbani, Anahita, Spagnolli, Ester, Martinez, Andrew, Ryan, Allicia, Tainsh, Laurel T., Kim, Samuel, Rong, Jian, Huan, Tianxiao, Freedman, Jane E., Levy, Daniel, Miller, Karen K., Hata, Akiko, del Monte, Federica, Vandenwijngaert, Sara, Swinnen, Melissa, Janssens, Stefan, Holmes, Tara M., Buys, Emmanuel S., Bloch, Kenneth D., Newton-Cheh, Christopher, Wang, Thomas J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726159/
https://ncbi.nlm.nih.gov/pubmed/23867623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI67383
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