The HLA–DRB1 Shared Epitope Is Associated With Susceptibility to Rheumatoid Arthritis in African Americans Through European Genetic Admixture

OBJECTIVE: To determine whether shared epitope (SE)–containing HLA–DRB1 alleles are associated with rheumatoid arthritis (RA) in African Americans and whether their presence is associated with higher degrees of global (genome-wide) genetic admixture from the European population. METHODS: In this mul...

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Autori principali: Hughes, Laura B., Morrison, Dahliann, Kelley, James M., Padilla, Miguel A., Vaughan, L. Kelly, Westfall, Andrew O., Dwivedi, Harshit, Mikuls, Ted R., Holers, V. Michael, Parrish, Lezlie A., Alarcón, Graciela S., Conn, Doyt L., Jonas, Beth L., Callahan, Leigh F., Smith, Edwin A., Gilkeson, Gary S., Howard, George, Moreland, Larry W., Patterson, Nick, Reich, David, Bridges, S. Louis
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726059/
https://ncbi.nlm.nih.gov/pubmed/18240241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23166
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