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A Systems-Based Approach to Investigate Dose- and Time-Dependent Methylmercury-Induced Gene Expression Response in C57BL/6 Mouse Embryos Undergoing Neurulation

BACKGROUND: Aberrations during neurulation due to genetic and/or environmental factors underlie a variety of adverse developmental outcomes, including neural tube defects (NTDs). Methylmercury (MeHg) is a developmental neurotoxicant and teratogen that perturbs a wide range of biological processes/pa...

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Detalhes bibliográficos
Main Authors: Robinson, Joshua F., Guerrette, Zachariah, Yu, Xiaozhong, Hong, Sungwoo, Faustman, Elaine M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726008/
https://ncbi.nlm.nih.gov/pubmed/20540155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdrb.20241
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