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Role for MicroRNAs in Regulating Glucocorticoid Response and Resistance in Multiple Myeloma

Glucocorticoids (GCs) are widely used in the treatment of hematological malignancies such as multiple myeloma. However, the development of resistance to GCs limits their clinical utility. Response to GCs is dependent on an active glucocorticoid receptor, GR-α, expressed at wild-type levels in the GC...

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Detalhes bibliográficos
Main Authors: Tessel, Michael A., Benham, Ashley L., Krett, Nancy L., Rosen, Steven T., Gunaratne, Preethi H.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725966/
https://ncbi.nlm.nih.gov/pubmed/21761344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12672-011-0072-8
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