Astaxanthin protects ARPE-19 cells from oxidative stress via upregulation of Nrf2-regulated phase II enzymes through activation of PI3K/Akt

PURPOSE: Oxidative stress on retinal pigment epithelial (RPE) cells is thought to play a crucial role in the development and progression of age-related macular degeneration. Astaxanthin (AST) is a carotenoid that shows significant antioxidant properties. This study was designed to investigate the pr...

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Main Authors: Li, Zhongrui, Dong, Xin, Liu, Hongling, Chen, Xi, Shi, Huanqi, Fan, Yan, Hou, Dingshan, Zhang, Xiaomei
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725964/
https://ncbi.nlm.nih.gov/pubmed/23901249
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