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Nucleofection of Expression Vectors Induces a Robust Interferon Response and Inhibition of Cell Proliferation

The interferon (IFN) response, induced as a side effect after transfection of nucleic acids into mammalian cells, is known but inadequately described. We followed the IFN response, the fate of cells, and the possible mechanisms leading to this response in NIH3T3 mouse fibroblasts after DNA nucleofec...

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Detalhes bibliográficos
Main Authors: Huerfano, Sandra, Ryabchenko, Boris, Forstová, Jitka
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725941/
https://ncbi.nlm.nih.gov/pubmed/23745681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2012.1950
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