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Neurodegeneration in Friedreich's Ataxia: From Defective Frataxin to Oxidative Stress
Friedreich's ataxia is the most common inherited autosomal recessive ataxia and is characterized by progressive degeneration of the peripheral and central nervous systems and cardiomyopathy. This disease is caused by the silencing of the FXN gene and reduced levels of the encoded protein, frata...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Hindawi Publishing Corporation
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3725840/ https://ncbi.nlm.nih.gov/pubmed/23936609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/487534 |
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