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Neurodegeneration in Friedreich's Ataxia: From Defective Frataxin to Oxidative Stress

Friedreich's ataxia is the most common inherited autosomal recessive ataxia and is characterized by progressive degeneration of the peripheral and central nervous systems and cardiomyopathy. This disease is caused by the silencing of the FXN gene and reduced levels of the encoded protein, frata...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Gomes, Cláudio M., Santos, Renata
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Hindawi Publishing Corporation 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725840/
https://ncbi.nlm.nih.gov/pubmed/23936609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/487534
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