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Radiation response and regulation of apoptosis induced by a combination of TRAIL and CHX in cells lacking mitochondrial DNA: a role for NF-κB--STAT3-directed Gene Expression

Mitochondrial DNA depleted (ρ(0)) human skin fibroblasts (HSF) with suppressed oxidative phosphorylation were characterized by significant changes in the expression of 2100 nuclear genes, encoding numerous protein classes, in NF-κB and STAT3 signaling pathways, and by decreased activity of mitochond...

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Autors principals: Ivanov, Vladimir N., Ghandhi, Shanaz A., Zhou, Hongning, Huang, Sarah X., Chai, Yunfei, Amundson, Sally A., Hei, Tom K.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725824/
https://ncbi.nlm.nih.gov/pubmed/21440540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2011.03.012
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