Genetics of the low density lipoprotein receptor. Diminished receptor activity in lymphocytes from heterozygotes with familial hypercholesterolemia.

Using circulating mononuclear cells as a readily available tissue and using the rate of high affinity degradation of 125-I-labeled low density lipoprotein (LDL) as an index of cell surface LDL receptor activity, we have measured receptor activity in cells from 53 individuals. This group includes 32...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Bilheimer, D W, Ho, Y K, Brown, M S, Anderson, R G, Goldstein, J L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1978
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372581/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/205553/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI108980
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