Novel Bis-Indole Agents Active Against Multidrug-Resistant Acinetobacter baumannii

The in vitro activity of five novel Microbiotix bis-indole agents (MBXs) against 30 multidrug-resistant (MDR) A. baumannii (including 18 resistant to carbapenems) was evaluated. Overall, MIC(90)s ranged from 1-8 μg/ml, whereas those for imipenem were > 64 μg/ml. MBX 1196 was the most potent (MIC(...

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Main Authors: Jacobs, Michael R., Bajaksouzian, Saralee, Good, Caryn E., Butler, Michelle M., Williams, John D., Peet, Norton P., Bowlin, Terry L., Endimiani, Andrea, Bonomo, Robert A
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725720/
https://ncbi.nlm.nih.gov/pubmed/21146724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diagmicrobio.2010.08.014
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